A mitochondrial-derived vesicle HOPS to endolysosomes using Syntaxin-17
نویسنده
چکیده
Damaged mitochondrial content is packaged in mitochondrial-derived vesicles (MDVs), which are targeted for degradation through an unclear mechanism. McLelland et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603105) show that the SNARE Syntaxin-17 mediates MDV fusion with endolysosomes, promoting the delivery of mitochondrial cargo to lysosomes for degradation.
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عنوان ژورنال:
دوره 214 شماره
صفحات -
تاریخ انتشار 2016